Chinese Journal of Clinicians, Vol 6, No 7 (2012)

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The value of balloon-assisted endoscopy and capsule endoscopy for treatment and surveillance of small-bowel polyps in patients with Peutz-Jeghers Syndrome

NING Shou-bin, MAO Gao-ping, TANG Jie, JIN Xiao-wei, ZHU Ming, BU Xiao-hua, CAO Chuan-ping, ZHAO Jie, YIN Xin

Abstract


  Objective To assess the value of balloon assistant endoscopy(BAE)and capsule endoscopy(CE)for treatment and surveillance of small-bowel polyps in patients with Peutz-Jeghers Syndrome(PJS).Methods A total of 86 patients with PJS were scheduled for BAE and polypectomy.After BAE procedures and therapy,some patients underwent CE.BAE and CE findings(number,size,and location of polyps),polypectomy and complications were evaluated.Results Two hundred and thirty seven BAE procedures(per anal 95,per oral 142)were carried out in 86 patients with PJS.Multiple small-bowel polyps were found in all 86 patients and the majority of polyps(80%)were located in the proximal jejunum.A total of 1895 polyps of≥10 mm were detected,and 1342(71%)were endoscopically removed.After BAE procedures and polypectomies,CE were scheduled for surveillance of small-bowel polyps(35 of 86 patients,41%),32 small-bowel polyps(≥10 mm)were found in 17 cases.A total of 17 repeated BAE procedures were performed in 14 patients and 25 small-bowel polyps were found and endoscopically removed.A total of seven serious complications(3 small intestinal perforation and 4 bleeding)were observed.Conclusions BAE is a reliable procedure for the treatment of multiple small bowel polyps,and CE is an effective method for surveillance of small bowel polyps in patients with PJS.Combined use of BAE and CE have important value for treatment and surveillance of small-bowel polyps in patients with PJS.

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Chinese Journal of Clinicians