Chinese Journal of Clinicians, Vol 6, No 7 (2012)

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Tissue Doppler imaging for assessment of ventricular function in children with pulmonary arterial hypertension secondary to congenital heart diseases

LIN Yue-se, LI Shu-juan, LI Xuan-di, YAO Feng-juan, WANG Hui-shen

Abstract


  Objective To investigate the value of tissue Doppler imaging(TDI)in assessing the ventricular function in children with pulmonary arterial hypertension secondary to congenital heart diseases.Methods From Aug 2010 to Oct 2011,twenty children with pulmonary arterial hypertension secondary to congenital heart diseases,twenty children with congenital heart diseases not combined with pulmonary arterial hypertension and twenty-four healthy children underwent tissue Doppler echocardiographic evaluation of both left and right ventricular function.The peak systolic velocity(Sm),peak early diastolic velocity(Em),peak late diastolic velocity(Am),isovolumic contraction time(ICT),isovolumic relaxation time(IRT)and ejection time(ET)of the anterior tricuspid annulus and posterior mitral annulus were acquired from apical four-chamber view respectively.Tei index of left ventricle(LV)and right ventricle(RV)were measured.Results Compared with control groups,LV,RV Em and LV ET were lower,while LV,RV Am,ICT,IRT and Tei index were higher in children with pulmonary arterial hypertension secondary to congenital heart diseases.There was a significant positive correlation between RV IRT and systolic pulmonary arterial pressure(sPAP).Conclusions Both systolic and diastolic function of left ventricle and mainly diastolic function of right ventricle were impaired in children with pulmonary arterial hypertension secondary to congenital heart diseases.RV IRT can be used as an alternative non-invasive method to assess sPAP.

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Chinese Journal of Clinicians